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Hi Birgitta-A,
Sorry to hear about the drop in white cells. That's a pretty dramatic jump in red cells though. When John was on Exjade, he noticed a very small increase in red cells but nothing real notable. His doc did not think much about the effect or Exjade's potential at the time. But this was 3 years ago when no one was looking at it.
Sounds like Exjade could have two applications....one to chelate and another to boost red cells. It would be good to see a study to find out the lowest possible dose of Exjade that will boost red cells. I believe the first article is really addressing that iron-overload becomes the focus versus the MDS; and to prescribe Exjade based on just FE levels and not take into consideration the type of MDS, is not a "best practice". There are many things to take into consideration when deciding a treatment path.
BTW...thanks again for posting those abstracts this year
Marlene
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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