Hi vikasgoyal,
Revlimid is used to increase HGB. Myelosuppression (suppression of the bone marrow) is a common adverse effect for patients with the 5q chromosome aberration and low platelets initially is a sign of positive response for these patients.
In non 5q patients myelosupression often isn´t so severe.
http://bloodjournal.hematologylibrar.../1/86.full.pdf
Revlimid should be combined with Prednisone (30 mg/day) in tapering dose for better response.
Kind regards
Birgitta-A