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Old Sun Oct 6, 2013, 04:05 PM
riccd2001 riccd2001 is offline
Join Date: Aug 2010
Location: Burlington,Ontario,Canada
Posts: 186
From an earlier thread on ACE-536 (Feb.2013)

...There's still more to do but these are very encouraging words in the PR...

"In a phase 1 clinical study of healthy volunteers, ACE-536 produced a dose-dependent increase in red blood cells and hemoglobin levels. "
Ric: Low-risk MDS (blasts <4%); 4 cycles Revlimid no positive response; PRBC transfusion dependent; so far, 392'units' over 8 3/4 years; BMB #4 (15/04/01) shows evolution to AML (blasts 20-30%) 47,XY,del(5) (q22q35),+21[24][cp24]/46,XY(1).
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