Originally Posted by Sally C
In a recent study comparing young unrelated donors with HLA-matched siblings, the European Group for Blood and Marrow Transplantation found that donor age of less than 30 years significantly improved survival in elderly MDS patients only for those using unrelated donors. Donor age had no impact on survival for those using HLA-matched siblings.
According to Dr. Kroeger, this finding indicates that for elderly MDS patients, a young unrelated donor is preferred over an HLA-matched sibling, which is preferred over an older matched unrelated donor.
That's something I learned at the AA&MDSIF Patient Conference in Los Angeles last month, and it surprised me that a matched sibling was not the first choice of donor. But the statistics show that a young matched unrelated donor is even better.