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Old Tue Apr 8, 2014, 12:14 PM
Chad S Chad S is offline
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Join Date: Jul 2013
Location: Dallas, Texas
Posts: 17
jessinpdx,
She did not go on Vidaza. MD Anderson is doing a trial on a drug called SGI-110, and she had 2 cycles (each cycle is 28 days). Her blasts dropped to 5% and a match was found (unrelated donor 10/10 match) so they proceeded with the transplant. SGI-110 is similar to decitabine but has a longer life in the blood stream.

Interestingly, MD Anderson is doing another trial that we elected to participate in where Vidaza is given after the transplant even if transplant shows remission. They are studying to see if Vidaza post transplant decreases relapse rate in high risk MDS cases. Unfortunately, my wife was randomly selected to not receive the Vidaza in the study. So she is included in the comparison group to the people the do receive the Vidaza.

I have heard good results from Vidaza and many people in this forum can share their experience with you.
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Chad, husband of Danielle age 39, diagnosed MDS (RAEB-1) Feb 2013, BMT May 2013
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