ATG side effects vary - definitely have your wife accept all pre-medications to help with them. I was treated with ATG prior to transplant, and it is the only thing that I have done that made me feel awful - severe flu-like symptoms that went away for me after two days. Here is a link from UPMC that lists the most common issues with treatment:
http://www.upmc.com/patients-visitor...-globulin.aspx
From what I have seen, results vary. A lot of people take cyclosporin with ATG treatment, especially for AA. Results can take anywhere from 1 month to 9 months to begin
Here is a pretty good article on AA treatments, side effects, and effectiveness:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138728/
This article gives more specifics about timeline:
http://www.aamds.org/treatments/ther...essive-therapy
Hope this info helps.
Dan