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Old Wed Jan 19, 2011, 02:41 PM
Neil Cuadra Neil Cuadra is offline
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Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,553
Thanks for testing the tool. We fixed the computation for the case of a single chromosome abnormality.

The tool follows the definitions in Dr. Greenberg's original article: International Scoring System for Evaluating Prognosis in Myelodysplastic Syndromes, Blood, Vol 89 No 6, 1997, which defines the karyotype categories as follows:
Good, normal, -Y, del(5q), del(20q); Poor, complex (>=3 abnormalities) or chromosome 7 anomalies; Intermediate, other abnormalities.
Trisomy 8 is not itemized, so it falls into the "other abnormalities" category under the IPSS. The newer IPSS-R system specifically itemizes trisomy 8.
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