Hi Dave,
Here is an interesting abstract about IST for older patients. Perhaps your mother's doctor can get the whole article for you as it seems very relevant to your concerns:
http://www.ncbi.nlm.nih.gov/pubmed/19062343
I did not notice an increase in my infection rate while on high-dose cyclosporine. However, it is important to take extra precautions (increased hand washing, wear a mask if necessary, avoid crowds, avoid sick people, etc). The concern is that if she got an infection, in could quickly become a lot more serious because of her compromised immune system.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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