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Vidaza and Blood Transfusions
My husband was diagnosed with MDS in May 2010. He was treated with Aranesp and Neulasta until late August when he started on Vidaza (the Aranesp and Neulasta are also continuing as needed). He had his first red blood cell transfusion in July. He has had 4 more since then, most of which were 4-6 weeks apart. However, 2 weeks ago he had a transfusion that really never seemed to "kick in." He had another yesterday and so far has not felt any improvement. I am wondering if this is part of the suppression that Vidaza causes in the beginning, or is it possible for red blood cell transfusion to quit working? If so, then what??
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Alice, wife of John, diagnosed MDS RAEB-1 5/10. Tried Vidaza, ON 01910.Na (at NIH), & Vidaza + Revlimid with no effect. Progressed to RAEB-2. Supportive care only from 9/2011 until death 1/26/12.
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