Thread: To Begin MDS Treatment? And with what?
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Old Sun Dec 26, 2010, 03:08 PM
Hopeful Hopeful is offline
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Join Date: Jan 2009
Location: California, USA
Posts: 766
Hi Dan,

I'd get another doctor/opinion involved, as I tend to agree with you...immune suppressant therapy can be very effective for MDS with a trisomy 8 mutation.

http://bloodjournal.hematologylibrar...hort/106/3/841

Since you are not transfusion dependent, cyclosporine alone (vs ATG) may be a viable less risky option. Follow Lisa V's threads for a good success story with a a similar situation.

Best of luck!
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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