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Hi Rui,
I would also recommend getting another opinion on the case. It is very hard to tell the difference between MDS and AA in the absence of chromosomal abnormalities in a hypocellular marrow. It would be good to have another pair of eyes reviewing the BMB slides or even possibly redoing the biopsy. AA is rarely seen in the elderly, and it would be prudent to confirm the diagnosis as well as to get another opinion on the next course of treatment.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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