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ASH 2011 - L-Leucine Improves the Anemia of the 5q- Syndrome Via Activation of the mT
http://ash.confex.com/ash/2011/webpr...aper43073.html
970 L-Leucine Improves the Anemia of the 5q- Syndrome Via Activation of the mTOR (mammalian target of rapamycin) Pathway
Good News for the 5q-Syndrome (and Patients with Diamond Blackfan Anemia):
"In a case report, administration of L-Leucine to a DBA patient resulted in complete recovery of the anemia and improvement in appetite and growth parameters. We therefore hypothesized that L-Leucine could improve the anemia associated with heterozygous loss of RPS14."
"Our studies support the further evaluation of L-Leucine as a potential therapeutic agent in the treatment of the 5q- syndrome."
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Margarete, 54, living in Vienna, Austria,
MDS/AML M2, diagnosed 9/2007, then Chemos, aSZT 4/2008, chronic GVHD
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