Hi All,
In this article they show that patients with several different chromosome aberrations - not only del5q - can respond well when they are treated with Revlimid. Some patients were treated with Revlimid in combination with Vidaza. As you can see the patient groups are very small:
"The most frequent cytogenetic abnormality among the patients who received Revlimid was gain of chromosome 8 material (6/42), followed by the loss of chromosome 20 material (5/42). Patients with gain of chromosome 8 had high overall response rate to Revlimid (5 out of 6, 83%) and overall response rate in patients with chromosome 20 abnormalities was 3 out of 5."
http://www.jhoonline.org/content/pdf/1756-8722-5-4.pdf
Kind regards
Birgitta-A