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Old Thu Nov 6, 2008, 04:29 PM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
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Nplate can increase blast cells in MDS patients

Hi Trudy,
Nplate (AMG 531) has given increased blast cells in MDS patients - donĀ“t try that drug if you have MDS! Look at these lines:

"In a separate single-arm clinical study of 44 patients with myelodysplastic syndromes (MDS), 11 patients were reported as having possible disease progression, among whom 4 patients had confirmation of acute myelogenous leukemia (AML) during follow-up.

Nplate is not indicated for the treatment of thrombocytopenia due to MDS or any cause of thrombocytopenia other than chronic ITP."


http://www.drugs.com/nplate.html
Kind regards
Birgitta-A
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