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I understand that the fluctuations in all counts are pretty wild sometimes post transplant. The low WBC is probably more a function of the GVHD as opposed to the steroids. I am assuming that you are speaking of something like prednisone.
"Corticosteroids have a profound effect on the concentration of peripheral blood leukocytes. Lymphocyte, monocyte, and basophil counts decrease in response to corticosteroid administration, while neutrophil counts increase."
Cyclosporine also has the impact of attacking lymphocytes, but not necessarily neutrophils.
Best thing to do is call the clinic and ask them your questions so that they can tell you what they think is going on and see if it is a concern or considered normal in their experience.
Another possibility is that the other immune suppressive drugs may need some adjustment.
Good luck getting to the bottom of this.
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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