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Old Thu May 9, 2013, 01:54 PM
Neil Cuadra Neil Cuadra is offline
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Join Date: Jul 2006
Location: Los Angeles, California
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One conference paper I find particularly interesting is Did the prognosis of MDS patients improve during the last 30 years? by J. Neukirchen et al.

They did a large survey to see how median survival times for MDS patients changed over the decades. The most significant trend they found was that for patients with more than 5% blasts in the bone marrow who did not have an allogeneic transplant, median survival times was 50% higher in the last decade compared with the preceding two decades. This improvement applied to all age groups. The difference can be explained by the availability of new treatments and perhaps the increased success of transplants.

They found that the prognosis for MDS patients with at less than 5% blasts did not change significantly over the same time period, presumably because treatment approaches such as supportive care for patients with low-risk MDS haven't changed as much over the years.
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