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I highly reccommend you contact Dr.Brodsky directly to get your answer. There is a risk of infertility with High Dose Cytoxan as well as with BMTs. Dr. Brodsky can give you the latest statisitic and the names of other patients for you talk to as well. It can also depend on the age of the patient. Example....a women in her perimenapausal years may be at higher risk for the infertility side effect than a child. I know that low-dose, long term cytoxan has greater chance of causing infertility than the 4 day High Dose.
But don't quote me......If you want more info on High Dose Cytoxan, then it is so important to talk to the expert on it. It is a clinical trial and they are still collecting data on it so outcomes, long term side effect, etc is fluid. Dr. Brodsky is very upfront about the risk, outcome and side effects of the protocol.
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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