Hi Flyguy,
One other option to consider is Campath. There are currently a few clinical trials for it that you may qualify for:
http://patientrecruitment.nhlbi.nih....ticAnemia.aspx
One benefit of Campath is that it is given outpatient.
I am also below the "therapeutic level" for Cyclosporine. My system just metabolizes it too quickly. It was too toxic for me to increase the dosage any higher. I do think the low dose is still having a positive effect on my marrow.
There just aren't any hard and fast rules on what levels should be for bone marrow failure disease patients. Again, everyone is different.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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