[Marlene]

My husband did not have ATG to treat his SAA so I can't speak to the cyclo and prednisone. When John's ANC hit .5, they started pulling him off all the anti-biotics and ant-fungals one at a time. They would stop one and then watch to see if he spiked a fever over the next two days. If not, then they pulled another and so on. If he spiked a fever, then they would put him back on the one they just pulled. With your mother's ANC at 2.4, it's puzzling that they still have her on those. The anti-fungals and antibiotics are either being used prophylactically or to treat an active infection. If she does not have an infection, then an ANC of 2.4 is more than adequate to warrant her being taken off of them. That class of anti-biotic (which includes Cipro)is probably one of that last ones that I would have thought to use prophylactically. Levofloxacin should be used only for infections that cannot be treated with a safer antibiotic. Many docs use this class of drugs as first line treatment for infections and we always push back for a safer option. Especially if you have any central nervous system issues. One of the rarer side effects is tendon ruptures.

They left him on the acyclovir for six months after treatment.

It's difficult to challenge the doctor but if he has little to no experience with treating SAA, then I would seek a second opinion. Your doctor can also consult with the NIH, Dr. Young.