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ATG - Cyclosporine side-effects
Hello all,
My wife (36 years old, mother of 2 kids) was diagnosed with SAA end of October 2011. Since then, she had multiple transfusions (mostly platelets) and received her first ATG (horse serum) @ MD Anderson.
It's been 1 week since the ATG and she's been on Cyclosporine/steroid w. taper schedule/Neupogen shots. Her platelet is 2000, WBC is 2.2, and Hemo is 9.0.
As the days go by, she's getting more weaker. Cyclo pills are making it worse as she almost passes out after taking the pills (once at 9am and again at 5pm - 100mg each). She can barely walk. She's at her best condition way early in the morning when the cyclo is at its lowest concentration in her blood. She also had some mild hives forming on her legs and are since disappeared. Her hands and feet are so hot that she has hard time sleeping. She also had an itching problem couple of nights ago.
Are these normal responses to the AATG/Cyclo regime? We told the doctor and he seemed to be less worried about these effects than continuing her regime.
She's getting her platelets every other day.....
Thank you so much for your help...
David Kim
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