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Old Thu Dec 22, 2011, 01:29 AM
Hopeful Hopeful is offline
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Join Date: Jan 2009
Location: California, USA
Posts: 766
Hi,

Unless your husband is a very small man, he may be at too low a dosage of cyclosporine. A typical therapeutic dose is 4-5 mg/kg/day. A dose of 180 mg/day would be a typical therapeutic dose for a 45 kg (or 99 lb) person. So perhaps that is why he keeps relapsing??? Perhaps the cyclosporine dosage is too low to make a difference, and he is relying mostly on the ATG effects.
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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