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Old Fri Mar 1, 2013, 10:54 AM
dr.zhraa dr.zhraa is offline
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Join Date: Mar 2013
Location: Egypt
Posts: 2
Acquired amegakaryocytic thrombocytopenia

I have a case and I hope Marrow forum to add me to find the sure diagnosis.
The case:
female, 27y old, virgin, with menorhagia 3 months ago, no history of medication, there is purpura and echemotic patches on the arms and the face, no splenomegaly, but there is enlarged fatty liver by US.
CBC (wbcs 7.2, HB 6.6, Plat 10)
Blood film shows leuckoerythroblastic reaction.
BM aspiration shows slightly hypocellular BM, absent megakaryocytes, myeloid series are slightly decreased with normal morphology. Erythroid series are increased with decreased M/E ratio (1.1/1), some of them are binucleated. Lymphocytes are normal. no abnormal cells were detected.
I recmmend BM biopsy for the case
I suggest the case to be (acquirea amegakaryocytic thrombocytopenia)
is that true? and what are the other investigation I should do to that case?
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