[BobbyJD]

Hi, long time follower but first post. 20yr old sister has AA. Diagnosed June 2010, found by chance. Never had any symptoms and never needed one transfusion except while receiving ATG.

Anyway, after ATG (9/2010) and Cyclo taper for 1yr+ counts rebounded very quickly to normal. Since Feb 2013 Platelets have been trending downward (120 in Feb, as of today 7/10/13 they are 70). Now these are still good numbers in the world of AA however its a negative trend and getting us worried. Doctor wants to start Cyclo once platelets hit 50. He also wants to do another bone marrow biopsy just to be sure there is no progression into something else. By the way he is a specialist in AA at NYU.

My question; Is she headed out of remission? Has anyone seen their Platelet count drop in similar fashion and if so what was the out come? Do you think cyclo should be started sooner?? *other counts are fine, not sure of the numbers but I know they are acceptable and not dropping like the platelets.

One reason for concern is when she was first dx, platelets were the first to go...thanks for your thoughts!