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Old Sat Jan 28, 2012, 01:17 PM
Marlene Marlene is offline
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Join Date: Oct 2006
Location: Springfield, VA
Posts: 1,406
I came across these studies in Pub Med and one Cleveland Clinic article. Of course, they do not address transfusion in BM failure but based on their finding, you can easily see how this applies.

http://www.ncbi.nlm.nih.gov/pubmed/2...?dopt=Abstract

http://www.ncbi.nlm.nih.gov/pubmed/20299509

http://www.ncbi.nlm.nih.gov/pubmed/21545003

http://www.cap.org/apps/cap.portal?_...geLabel=cntvwr

Quote from the above article says it all ......

Stored blood and steak are both protein, Dr. Shander says, but a person would probably “think about 1,700 times before cooking and eating 42-day-old steak.” And while blood is sterile and probably not growing anything, it’s decaying as a protein for 42 days, he points out. “So why spend time arguing about whether the literature is equivocal on whether older blood is more harmful than fresher blood? There’s no question in anyone’s mind that the longer a protein decays, the less functional it is. And there are lots of other things in the blood—it’s basically a bag of immune complexes.”
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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