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Old Tue Aug 27, 2013, 10:58 PM
sbk007 sbk007 is offline
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Join Date: Apr 2013
Location: NY
Posts: 322
Quote:
Originally Posted by Greg H View Post
Hey Ann!

As I understand it, Vidaza and Dacogen both work in pretty much the same way. They are both "hypomethylating agents," which means they affect important processes at the level of DNA.
Greg
They are demethylators/hypomethylators. The idea being that hypermethylation(too many methyl chains) inhibits gene expression and by releasing the methyl chains the genes are able to express themselves.
I've had 4 rounds of Vidaza so far with great results, and no side effects luckily. My understanding is it depends on the docs you use and the experience they have with it For example if your treated at Cornell-weill they'll go with vidaza, over at mt Sinai they go with Dacogen. Hope that helps.

Last edited by sbk007 : Mon Sep 2, 2013 at 04:41 PM. Reason: .
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