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Old Fri Nov 11, 2016, 09:13 AM
Marlene Marlene is offline
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Join Date: Oct 2006
Location: Springfield, VA
Posts: 1,406
Aplastic Anemia is a diagnosis of exclusion and once they rule out all the other possibilities, they can then diagnose the anemia as aplastic anemia. Sometimes they call it pancytopenia meaning that all three blood lines are affected, red cells, platelets and white cells.

There are three diagnostic criteria of aplastic anemia:

Severe (SAA) - The bone marrow cellularity is <25% AND at least two of the following are met; Neutrophils <0.5; Platelets <20; and Reticulocytes <20.

Very Severe (VSAA) - Same as above but the neutrophils are <0.2

Moderate (which is not usually treated) - The bone marrow cellularity is <25% but the peripheral blood counts do not meet the criteria for SAA

Reticulocytes are new or immature red blood cells being made.

Hope this helps
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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