I don't think you can test for the protein before transplant. I think after transplantation they can test for it as an early indicator. That's the way I read it.
Not only is there t-cell depletion controversy(because although you might avoid gvhd, it might increase the risk of other things) but also the method used to deplete the t-cells is controversial. There's one drug called Prochymal that's approved in CD but I cant find much info on the clinical trials here.
|