Thread: Vit B12 levels
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Old Tue Nov 19, 2013, 09:44 AM
Marlene Marlene is offline
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Join Date: Oct 2006
Location: Springfield, VA
Posts: 1,406
Mseth,

Dont' know how helpful these will be. You can also post your question on their forum and see what response you get. Understanding hyper/hypo methylation at the gene level is still in its early stages. From what I understand, you can have both hypo and hyper occurring at the DNA level simultaneously. I'm not sure that it's about having too much of folate/B12, but more about where the breakdown is occurring in the DNA/RNA methylation patterns.

http://mthfr.net/methylfolate-side-effects/2012/03/01/
http://mthfr.net/how-much-methylfola...ke/2012/03/22/

It's really not as easy as one would think to figure this out. For us, I focused on making sure to add in B12 first, then the methyl folate, and then a B complex. Of course John is in a partial stable remission and really has no symptoms associated with MTHFR problems. But he's been at this, on some level, for the past 9 years.

Here's an article, just in case you need something to put you to sleep, on Caner and methylation. It sent my head spinning.

http://jco.ascopubs.org/content/22/2...ull.pdf%20html
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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