Thread: Copper levels
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Old Thu Feb 4, 2016, 11:34 PM
Cheryl C Cheryl C is offline
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Join Date: Dec 2011
Location: Lake Macquarie, Australia
Posts: 843
I posted these articles so that anyone newly diagnosed with MDS and having in particular, low neutrophils, is aware of the possibility of a copper deficiency - particularly patients with neuropathy and/or gastric complications.

NCBI - "We conclude that copper deficiency should be considered in all patients with unexplained anemia and neutropenia or myelodysplasia"

oxfordjournals - "copper deficiency is likely an underrecognized cause of anemia and neutropenia and may masquerade as a myelodysplastic syndrome (MDS)"

Haematologica - "We recommend copper level assessment in patients suspected of having low-risk MDS, especially those with gastrointestinal disorders and neuropathy."

Blood Journal - "copper deficiency should be an integral part of the differential diagnosis of sideroblastic MDS"

Chirley was diagnosed with MDS and when she received copper supplementation her MDS symptoms went away. Her posts are still available.
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Dx MDS RAEB 10% blasts + hypogammaglobulinemia, Sep 2011. Jan 2012 BMB - blasts down to 2% w/out treatment so BMT cancelled. Re-diagnosis RCMD. Watch and wait from Feb 2012. IVIg 5-weekly. New diagnosis Oct 2019 AML 23% blasts in marrow, 10% blasts in peripheral blood.
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