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Old Sat Nov 13, 2010, 01:02 PM
Lisa V Lisa V is offline
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Join Date: Aug 2006
Location: Waimanalo, Hawaii
Posts: 401
Dhruba, in the US the standard is: if the patient is young (less than 40 yrs.) and has an HLA matched sibling, then transplant is usually recommended. If there is no match, or if the patient is older, then IST (ATG + cyclosporine) is usually the first line of treatment. In order to make a decision, you will need to first find out if your wife's sister is a suitable match. If not, then IST is the next step. If that doesn't work, then it's time to search for an unrelated donor.

Is ATG treatment available in Bangladesh? The rate of success of cyclosporine alone is not nearly as good as it is in combination with ATG. I would be concerned about that.
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-Lisa, husband Ken age 60 dx SAA 7/04, dx hypo MDS 1/06 w/finding of trisomy 8; 2 ATGs, partial remission, still using cyclosporine
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