To my MDS colleagues,
Latest results incouraging.
BMB on 2/24/10 shows improved marrow cellularity: 45-50%, highest in several years, Blasts reduced to 14% from 35% on 10/09. Blood counts improved from minimums in 6/09. Hgb mid 10's-11's, platelets mid 20's-50's, ANC low at 300-600.
I'm still on the 3 drug regimen: Thalidomide 100mg/day, Dacogen 10mg/wk, Promacta 75mg/day. One Procrit 60k/wk, one Neupogen 480/wk.
We are not sure which drug is responsible for the improvements, but will not change the treatment plan until necessary.
The low dose Dacogen was recommended by the Cleveland Clinic, the one day/week dosage is being studed there by MDS researchers, the goal would be to move up to 20mg/day/wk. My doctor has had good results with Thalidomide and I responded to it as the first drug I tried in 2004.
I've had 6 years and counting, looking for a few more.