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Carol,
I'm sorry that you have to deal with this, but I'm glad that your MDS has been stable for so long.
Anemia is one of the possible side effects of ARIMIDEX, but I don't know that pancytopenia (having all three blood lines low) would be a likely result. Still, ARIMIDEX is a primary suspect since it's new to your regimen and you've already ruled out some other possible causes.
From what I've read, increased reticulocytes with MDS isn't common but isn't unheard of. For example, slow maturation of the immature red cells could be causing a buildup. The clues in your bone marrow are the likely key, so enduring a bone marrow biopsy should give you some answers.
Good luck to you, your husband, and your son.
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Founder of Marrowforums and caregiver for my wife
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