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Old Thu Dec 23, 2010, 12:17 PM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Nplate

Hi Mcgill,
Yes, the first report was quite alarming with several patients that got increased blast cells after 28 days. Then FDA warned about Nplate for MDS patients. Now I have seen reports where less patients develope AML after long term use of Nplate than MDS patients without Nplate.

Hi Maragarete,
Yes, a low dose of Nplate would probably be OK. Even for patients with Immune Thrombocytopenic Purpura (a bleeding disease) Amgen advices low doses - they should not try to get normal platelet counts.
Kind regards
Birgitta-A
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