Hi All!
I've been reading up on telomeres, TERT & TERC mutations, and bone marrow failure. I've found a couple of review articles that are available free in full text. Those of you who are, like me, inclined to occasionally torture yourself by trying to understand stuff that's way above your pay grade might find these interesting.
Telomere maintenance and human bone marrow failure, by Dr. Calado & Dr. Young of NIH
Telomeres and Marrow Failure, by Dr. Calado (This one is a PDF file.)
Have fun!
Greg
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Greg, 59, dx MDS RCMD Int-1 03/10, 8+ & Dup1(q21q31). NIH Campath 11/2010. Non-responder. Tiny telomeres. TERT mutation. Danazol at NIH 12/11. TX independent 7/12. Pancreatitis 4/15. 15% blasts 4/16. DX RAEB-2. Beginning Vidaza to prep for MUD STC. Check out my blog at
www.greghankins.com