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Congratulations on your husband's response to Eltrombopag!
I don't have personal experience with this drug but have read that in clinical trials they like to consider discontinuing it at 12 weeks if there is no response because of the risk of clonal evolution (specifically monosomy 7).
Is it possible to separate the Cyclosporine taper from the Eltrombopag taper in case the Cyclosporine is having any effect?
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
Last edited by Hopeful : Mon Jun 22, 2015 at 01:57 PM.
Reason: typo.
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