View Single Post
Old Fri Oct 27, 2017, 06:09 PM
worriedmama worriedmama is offline
Join Date: Apr 2017
Location: Austin, TX
Posts: 21
Anyone with similar experience?

Hi all,

So grateful to have this group! My 4 year old has unexplained normocytic/normochromic anemia and her hemoglobin averages around 9.5. She has periodic neutropenia (average seems to be 1200, sometimes dips to 800.) Retics .5%. Normal platelets. Normal copper and most other studies including FISH and chromosomes. Weak muscles which may or may not be related to her condition. She has much fatigue, low grade temps.

We recently had her latest bone marrow biopsy slides reviewed by a different institution and this is what we got back:

"The mild megaloblastic changes of erythroid precursors are of uncertain significance, particularly given her red blood cells in the blood stream are of a normal size. The rest of the cells look normal. She has had studies performed here and at her home institution for disorders that can lead to megaloblastic changes (e.g., vitamin B12 levels) but these have been normal. I do suspect that the change in the appearance of the erythroid (red cell) precursors and her anemia are related but it is not clear what the underlying cause is yet."

Does anyone have any related experiences or insights?

Reply With Quote