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Old Thu Dec 6, 2012, 06:04 AM
Greg H Greg H is offline
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Join Date: Sep 2010
Location: North Carolina
Posts: 660
Thanks, Birgitta!

There's a poster or oral presentation at ASH that describes a bit of what the folks at NIH have found by screening folks for shorter telomeres and related genetic mutations.

Screening all their bone marrow failure patients since 2003 for those issues, they found 114. I asked how many in total they had screened. I didn't get that answer, but I did get a rough ballpark guess that roughly 10% of bone marrow failure patients have telomere problems.

Flipping that around, the ASH presentation finds that the great majority of bone marrow failure patients who do have telomere problems have aplastic anemia. Only 11% had MDS.

Take care!

Greg
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Greg, 59, dx MDS RCMD Int-1 03/10, 8+ & Dup1(q21q31). NIH Campath 11/2010. Non-responder. Tiny telomeres. TERT mutation. Danazol at NIH 12/11. TX independent 7/12. Pancreatitis 4/15. 15% blasts 4/16. DX RAEB-2. Beginning Vidaza to prep for MUD STC. Check out my blog at www.greghankins.com
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