Quote:
Originally Posted by hxmxsx
It has been 200 days since my husband underwent h-ATG treatment. His blood work shows little response: Plt: 18, Hgb: 7.7, WBC: 2.4 and ANC 0.9. He is on cyclosporine 525 mg/day (about 6mg/kg/day). The doctor is concerned about his kidney level. Creatinine: 1.62. He is also on Eltromobag 50mg for 2 weeks now. The doctor will reduce his Cyclosporine by 25 mg starting today and will increase his Eltromobag to 100mg.
The doctor is very straightforward with him. If, by the time he is not responding to Eltromobag 150mg which is about 4 weeks from now, he will have to go through r-ATG.
By the way, his platelet transfusion (1 unit) was on 11/23/2014 and his last RBC transfusion (2 units) was 10/28/2014.
Any comments are welcome as we are not optimistic. Thanks.
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I am sorry that your husband didn't have a further response yet. Here is a recent article about the treatment of refractory AA. I hope things turn for him.
http://asheducationbook.hematologyli...2013/1/87.full
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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