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Lower Dose Vidaza
Hi Francine,
Brigitta is correct, the dosage for Vidaza can and is often reduced depending on the health of the MDS patient.
I recently started on a 3 day dose of 50mg/m2, this is only 40% of a "5 day dose schedule of 75mg/m2/day". The 5 day dosage is gaining in popularity and is working for some MDS patients. My dosage was started low due to my low platelets and bone marrow cellularity (10-15%), my doctor talked to several other MDS center of excellence doctors for ideas on the dosage.
Celgene personnel can help find other doctors to consult with on Vidaza dosages.
I've talked to a lady in her 70's who is doing great on a 5 day cycle, and older gentleman is doing great on the same 5 day cycle.
I will start a 5 day dosage next week since my counts have held up well.
Vidaza has really helped many MDS patients, keep a positive attitude and encourage your Mom.
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Kirby71, RAEB2 dx 2/04, Thalidomide 30 mo, Revlimid 18 mo, No resp Vidaza
6/09 2nd Thalid use, Promacta, Lowdose Dacogen added 10/09 at 40% blasts. 5/11 BMB-blasts 8%.
2/11 2nd Revl restart=good resp, Platelets drop 6/11, 3rd Thalid,+Nplate+Dacogen. 7/12 Cnts stable for 10 mo.
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