Quote:
Originally Posted by Ruth Cuadra
Blast counts can be measured in the blood and bone marrow, but iron stains are needed to detect ringed sideroblasts.
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So part of the diagnosis of MDS is sideroblasts; not having enough iron in the marrow means this part of diagnosis can not be made.
Somebody said earlier that if cytogenetics are normal, then ironclad diagnosis can not and should not be made.
If blasts are below 5%, that is still normal, no?
But if AA reduces the number of cells, and leukemia increases it (usually), then having various combined problems with cell lines should be left with - MDS, by exclusion?
However, immunophenotyping by flow cytometry should be able to pinpoint the types of problems or atypical cells/cell lines who can read that kind of stuff?
-Just trying to make sense out of things..