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Big dosage!
Wow, that's a big dosage! When I saw Dr Paquette, he said there was no established therapeutic dosage, but he mentioned 5 to 15mg per kilogram as a range. Based on my calculations, I weigh 113 kilograms. At the low end, my dosage would be 5 x 113 = 565 mg per day. And yet I only take 400mg per day. (That is why I would like to increase my dosage to try and bump up those pesky platelets before we start a taper, and Dr Paquette is not against the idea; the risk is creating a problem with my kidneys).
Your doctor may be putting too much emphasis on maintaining a certain trough level. What I have heard is that the trough is not that much of a guide in this process.
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Male, 56, dx Nov2006 VSAA (BMA:0%). Responded to ATG/CsA/Prednisone/Neupogen Dec 2006, but relapsed in June 2007. Counts are responding to using CsA 200mg bid alone since Jun 2008. Last PRBC tx: Jul 2008.
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