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Old Thu Nov 8, 2012, 05:52 AM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Ferriprox and Exjade

Hi Teo,
Your mother's ALT is not very high - I should not worry about that. It is probably an effect of one of her drugs. LDH is high in many cancer diseases and we can't do much about that.

Ferriprox leads to low WBC more often. The most important WBC are the neutrophils. Low neutrophil count is called neutropenia.
http://www.accessdata.fda.gov/drugsa.../021825lbl.pdf

Exjade can give low WBC but it is not common. Exjade has other adverse effects but as far as I understand they are not so dangerous as neutropenia.
http://www.us.exjade.com/health-care...g-patients.jsp

When my WBC started to decrease Ferriprox was stopped and I continued with Desferal in connection with txs. When my WBC was OK - at that time I did take 2 Neupogen injections/week - I started with a very low dose of Exjade and could never take as much as I should according to my weight due to decreasing WBC.
Kind regards
Birgitta-A
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