Thread: RUNX1 gene
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Old Tue Nov 14, 2017, 07:28 PM
Data Data is offline
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Location: Florida
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Runx1

The following is from the web site:
http://www.genecards.org/cgi-bin/carddisp.pl?gene=RUNX1

RUNX1 is a transcription factor that forms a complex with the cofactor CBFB. This complex provides stability to the RUNX1 protein which is involved in the generation of hematopoietic stem cells and for their differentiation into myeloid and lymphoid lines. Loss of RUNX1 function has been shown to impair differentiation between myeloid and lymphoid lines often resulting in the development of leukemia.

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