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Old Sun Dec 12, 2010, 02:16 PM
Lisa V Lisa V is offline
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Join Date: Aug 2006
Location: Waimanalo, Hawaii
Posts: 401
Thanks for posting that link, Hopeful.

I'm with the others in pushing for a slower taper. My husband is one who relapsed after a quick taper, and we had to start all over again. His doctor at the time didn't think it would matter, but I suspect he was more familiar with cyclosporine use in organ transplant patients than with the unique dynamics of ATG/cyclo and AA patients. If you can show your doctor some hard evidence in the form of a study, you may be able to have a more productive conversation.

I like Neil's idea of playing it by ear based on test results. That in itself would probably necessitate a slower taper in order to make sure your counts have stabilized at each level before making the next reduction. Seems like a common sense approach, and if you are not currently having problems with creatinine or blood pressure from the cyclo, I don't think the added risk of prolonging it a bit is enough to outweight the risk of relapse.
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-Lisa, husband Ken age 60 dx SAA 7/04, dx hypo MDS 1/06 w/finding of trisomy 8; 2 ATGs, partial remission, still using cyclosporine
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