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Old Fri Jul 29, 2011, 08:14 AM
JodyW JodyW is offline
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Join Date: Jun 2011
Location: westerville, ohio
Posts: 56
Cyclosporin Taper?

My question is about tapering. Trevor began ATG/Cycl treatment in March and was on 700 mg Cyclo. 350 2x day. On May 1 he was dropped to 350 mg 1x per day. I was able to speak with a Dr. who saw him at the clinic and discussed why he was not on the 350 given 1/2 every 12 hours. He agreed it should be that way and changed his dose to 175 2 x day. He also said Trevor's level's were good at 267. and he wanted them between 100-300. (not sure what that level is but he said it says the cyclosporin is at the right amount). But then he said he was going to start to taper him 50 mg a month beginning next month.

So questions-
When does one start to taper?
What does a normal taper look like?
What do you look for to make sure its not to much?
How low do they go with a taper?
I read on another tread that it can cause a replapse, what should one be looing for to determine how its going?
Trevor's last cbc was WBC 2.3, Plt. 90 , Hg 8.9. At what levels does one look to do a taper?


Thanks,
__________________
Jody, mother or Trevor 23. Diagnosed VSAA 3/11 , ATG cyclosporin 3/11 response 6/11, Relapse 1/13, Round 2 ATG 1/13
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