[akita]

Hi Birgitta,

You know many patients with low platelets don't get better after platelet transfusions because the new platelets are destructed at once. Even if they try HLA matched platelets the platelet count can be very low.

This sounds tragic.

So there are people who don`t response to or tolerate platelet infusions because of preexisting immune thrombozytopenia,

and on the other side people who develop a sort of seconday platelet-immunity.. (?)

Another problem, different of that getting access to platelet transfusions in case of high probably bleeding danger, but platelets higher than 10.000,00, 20.000.

>In Sweden PFA 100 is used at most clinics but I don't know my value because when I got my dx they only used bleeding time that was supposed to be valueless but they didn't have any better methods.

Is this different now, - do they have better methods?

I read about full blood platelet aggregation tests that should be of advantage. Have you heard about it?

When i got several platelet transfusions during chemotherapies and transplantation, the doctors were aware of different platelet triggers according for the special treatment i needed (and of course in case of to low platelet count in generally). For a BMB you needed 20.000 platelets. The transfusions caused no problems and i responded well.

How is this situation in a hematological ward in treatment for aplastic situations during therapies different from that of the "long time platelet" patients...


Thank you very much for your informations and dialogue.

Kind regards,
Margarete


>My bleeding time was more than 21 minutes - they didn't measure more than that.

That should have been clear enough. Your platelet functionning was seemingly bad.