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Old Thu Oct 10, 2013, 12:28 AM
Hopeful Hopeful is offline
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Join Date: Jan 2009
Location: California, USA
Posts: 766
Hi Steph,

What is your brother's dosage of cyclosporine, and what is his weight?

Are they taking cyclosporine trough measurements to ensure that he is not at too toxic a level?

Pay attention to your brother's creatinine. Ideally, it should not rise more than 30% of its pre-ATG levels.

Make sure that he drinks plenty of water!!

Although cyclosporine can cause sub-clinical damage to the kidneys, the effects on creatinine can be reversed when the dosage is lowered. If the dosage is appropriate for a person's body weight, there is less chance of problems. Just remember that more-is-not-always-better when it comes to this drug.

Hope he starts feeling better!

P.S. I love France
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55 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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