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Hepatitis and BMT
My hubby is 71 and was diagnosed with MDS in March 2011. His is treatment-related, trilineage, 7q deletion/monosomy 7. Came from treatments for NHL, starting in 2001. He acquired Hepatitis B (probably from transfusion in 2002?) and had a bone marrow transplant in 2008 (this was to kill the NHL; long before MDS came along) at age 66/67 (actually, his 67 birthday was the day before the transplant). He had already been on one medication to suppress the HepB (for several years) and started on a second one 4-5 months prior to the transplant. I know that, at least in his case, the fear was that the transplant (and treatment leading up to it) would reactivate the HepB. The two meds were to prevent that, and he is still on them. We tried coming off about two years ago but the HepB started to reactivate . . . not worth it. The BMT was definitely no walk in the park, and it was a long recovery, but he made it.
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hubby 73, dx NHL 2001, CNS involvement. SCT (auto) 5/08 [dx UTUC renal pelvis, 2010/surgeries/MMC], MANY recurrences, chemos, surgeries, rad. dx t-MDS 3/11: IPSS 1.5 (Int-2); MDA 11, RCMD trilineage, inc. Fe, ring sideroblasts, 7q del/mono 7 (51.5%), 46,XY,t(6,17)(p22;q25)[4]/45,XY,-7[4]/46,XY[12].
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