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Old Fri Jan 28, 2011, 04:03 PM
Birgitta-A Birgitta-A is offline
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Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Revlimid

Hi Susan,
Revlimid is an immunmodulating drug similar to Thalidomide but should not give neuropathy like Thalidomide can do.

Here is a study about Revlimid (Lenalidomide) in patients without isolated 5q- chromosome aberration. The results are best in patients with that chromosome aberration - about 70% respond.

In this study they didn’t give the patients Prednisone in tapering dose during the first 3 months - I don't know why because that is supposed to increase response.

As you can see 42% of the 31 low risk patients obtained a red blood cell response according to international criteria.
http://ash.confex.com/ash/2010/webpr...aper27957.html
Kind regards
Birgitta-A
71 yo, transfusion dependent since dx 2006 but no transfusions after 3 months treatment with Thalidomide Sept 2010.
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