|
The rate of conversion of AA into MDS is in single digits if the initial screening was done right (BM biopsy plus FISH for chromosomes 5, 7 and 8). Trisomy 8 does happen after ATG, and the clone serves as an ongoing irritant for the immune system which suppresses the marrow. Monosomy 7 carries a bad prognosis.
If concerned about MDS, you should talk to your doctor about repeating a BM biposy and cytogenetics. Unfortunately a Hgb of 8 will make an adult feel tired, irrespective of the cause. Procrit and Aranesp can give you a boost in Hgb, but are not a solution to low Hgb, but rather a short term fix.
Hope this helps.
Dan
|